(For you ultra-purists out there, sure, maybe it’s not super low carb, but it’s certainly low carb compared to the standard American diet, no?)
My guess is that some of the people who claim low-carb killed their thyroid, derailed their menstrual cycle, and all that other stuff, were following very low carb diets while also overtraining, not sleeping enough, having other sources of mental & emotional stress, and very likely, most probably, ding-ding-ding, we have a winner -- not eating enough total calories. Women of all ages, but particularly, young women, tend to fall into this calorie hole. Was it low-carb that derailed their hormones, or was it trying to burn not one candle at both ends, but more like ten candles at three ends (if that
’s even possible), while basically starving themselves? Whether or not they were aware of it, that may be what was happening: at a cellular level, they were starving. (Even if they didn't feel especially hungry throughout the day. I’m talking about the cellular level, where we’re not always cognizant of what’s going on.)
In the few diet studies that actually show "success," LC = sufficient for obese IR; full-keto unnecessary for ↓BW. @tednaiman @recomphacks— Bill Lagakos (@CaloriesProper) July 7, 2015
There are some people who will benefit from going the extra mile and adopting a true ketogenic diet -- or, really, in some cases, just an "ultra low carb" diet, as Kiefer might call it. Aside from the obvious ones (cancer, Alzheimer’s, epilepsy, and other neurological conditions, such as MS and ALS), other conditions that might (might) respond exceptionally well to a ketogenic approach are mood/psychological disorders, the management of which may depend on optimizing brain function and neurotransmitter levels.
As for the ongoing mudslinging between the various factions of Paleo, Primal, low carb, and keto, I stand by what I’ve always believed: we agree on so much more than we disagree on. The primary underlying principles of all of these approaches basically overlap: reduce or eliminate grains, refined sugars, processed foods, and vegetable & seed oils; focus on good quality animal foods; don’t fear naturally occurring fat. The rest—FODMAPs, salicylates, the gut biome, whether or not plant foods are essential—is just details. We have enough to debate from the camp that thinks endless acres of corn and soybeans—and the imitation meat products made from them—are the salvation of the entire human race and all the ecosystems on Earth. I’d like to see us stop wasting time and energy fighting among ourselves.