Is Insulin Messing with Your Skin?

Question: Is there anything in the body insulin doesn’t affect?

Answer: From what I’ve seen, no.

If you’re new to my blog or are a newcomer to the science of the clinically therapeutic effects of dietary carbohydrate restriction, you might think of insulin mostly as a blood sugar hormone. People with diabetes have blood sugar that’s too high, so they take insulin to bring it down. Simple, right? Not quite.

I’ve written in past posts that reading and learning I’ve done over the past few years has led to me to the perspective that lowering blood sugar is among insulin’s least important effects. (In fact, insulin isn’t even required to lower blood sugar at all. Your body can do that just fine without insulin…even in someone with type 1 diabetes. Type 1 diabetics do need insulin, just not solely for the purpose of lowering blood sugar. Details on all this here.)

I’ve written articles about insulin as a major factor in the development of gout, migraines, Alzheimer’s disease, PCOS, erectile dysfunction, benign prostatic hyperplasia (BPH, a.k.a. enlarged prostate), Parkinson’s disease, and more. The short list of things we know for certain are damaged by chronically elevated insulin and/or blood glucose (BG) includes the liver, kidneys, eyes, cardiovascular system (heart muscle and blood vessels), ovaries, the brain and nervous system. At this point, knowing what I now know about insulin, I don’t need someone to explain to me why insulin would affect any particular organ, gland, or tissue system; I need them to explain why it wouldn’t.

With this in mind, is it possible insulin is affecting your skin? You can’t see a fatty liver, polycystic ovaries or an enlarged prostate gland from the outside; you need special tests to determine for sure whether you have those. But what about acne, skin tags, psoriasis, and other things we can see just by looking at someone? Could insulin be playing a role here, too?

Tl;dr: If you want a brief summary of this article, read this. And if you have a few extra minutes and want to read one paper that will give you an enormous amount of insight into this topic, read this one. But if you come to my blog because you enjoy digging into the meaty details, stay here and keep reading. 

The PCOS Post: Hormonal Havoc From Hyperinsulinemia

As I mentioned in the previous post, I’ve been plugging away this blog since 2012. It’s hard to believe it’s been seven years, but even harder to believe that in all that time, I’ve completely neglected the topic of polycystic ovarian syndrome (PCOS). I’ve written a ton about insulin, glucagon, thyroid hormones, digestion, cancer, and more, but not one word about PCOS, except for a brief mention in this post. This is a glaring omission, because PCOS is a huge issue for reproductive aged women these days, and, no surprise if I’m writing about it here, it’s intimately tied to chronic hyperinsulinemia and metabolic dysregulation.

A while back I wrote about the effect of elevated insulin on men’s hormones, explaining the concept of a “male equivalent to PCOS,” and I didn’t realize that I hadn’t even yet written about actual PCOS. I don’t know how such a huge gap has existed on my blog for so long, but this is being corrected right now. Whew!

I’ve seen online in various places women saying that they’re at increased risk for type 2 diabetes or metabolic syndrome because they have PCOS. It’s actually the other way around: chronically high insulin (basically metabolic syndrome, whether you know you have it or not) is the main driver of PCOS. The reason so few women who have PCOS are aware of this is … surprise, surprise … most doctors are clueless about insulin’s many functions unrelated to blood sugar and they never bother measuring insulin levels.

Women with PCOS are often given unhelpful and condescending advice.  There is a lot of "blame the victim" that goes on with this condition. I sincerely hope this post does not come off that way. That is the very last thing I intend. I have only one goal here: to provide information. Information that can be empowering to women who have PCOS. If you are living with this condition and you feel disappointed by the help you've gotten from healthcare professionals so far, please know that you can take control. You have more power than you might realize. I hope what follows here is helpful.   

This is a long post (some of you are rejoicing now and others are groaning), so grab yourself a beverage of choice, a bag of pork rinds or some string cheese, and happy reading!